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The mind is inspired through physical (touch) and sensory perceptions and it focuses the muscle of the penis to chill out and this improves blood flow to the penis.
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Four experiments were conducted. Experiment one examined the effect of L-NMMA on NMDA mediated behavioral responses in normal rats; experiment two measured behavioral responses to NMDA or sodium nitroprusside (SNP), an NO donor in both control and diabetic rats; the third experiment observed the effect of diabetes on nNOS protein in the PVN; the fourth experiment measured NMDA mediated behavioral responses in diabetic rats after restoring the nNOS protein in the PVN using viral gene transfer.
In previous research, the Wake Forest researchers engineered human bladders in the lab. In clinical trials, about 30 children and adults with congenital bladder abnormalities or bladder injuries who were treated with the engineered tissue showed normal or improved bladder function for nearly 10 years, Atala said. Other researchers have shown some success in clinical trials with transplanting windpipe tissue.
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Vascular function within the penis can be evaluated with duplex ultrasonography. Patients are administered an intracavernosal test dose of a standard vasodilator, such as 20 mcg of prostaglandin E1 (PGE1), and the cavernosal arteries within the corpora are measured before and after the injection. A normal response indicates a peak systolic velocity of 0.35 m/s or more and an end diastolic velocity of -0.04 m/s or less. This is interpreted as adequate arterial blood flow (good peak systolic velocity) without evidence of a venous leak (end diastolic velocity below zero).
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