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Erectile Dysfunction Health Center
Transurethral alprostadil provides the same significant improvement in erectile function as injectable alprostadil with a better tolerated method of delivery. In one large study,15 65 percent of patients reported successful and satisfactory intercourse. This form of alprostadil is thought to diffuse into the corpus spongiosum and then into the corpus cavernosum. Once the drug enters the cavernosum, the arteriolar smooth muscle relaxes, resulting in erection. In a large double-blind, placebo-controlled study, the most common reported side effect was penile pain (10.8 percent), which was not judged by patients to prevent its use.15
Herbal Medicine for Erectile Dysfunction: -
Alarmist Advice or Scientific Proof?
Men's perceptions of masculinity differed substantially from stereotypes in the literature. Men reported that being seen as honorable, self-reliant, and respected by friends were important determinants of self-perceived masculinity. In contrast, factors stereotypically associated with masculinity, such as being physically attractive, sexually active, and successful with women, were deemed to be less important to men's sense of masculinity. These findings appeared consistently across all nationalities and all age groups studied. For quality of life, factors that men deemed of significant importance included good health, harmonious family life, and a good relationship with their wife/partner. Such factors had significantly greater importance to quality of life than concerns such as having a good job, having a nice home, living life to the full, or having a satisfying sex life. Of note, rankings of constructs of masculinity and quality of life did not meaningfully differ in men with or without erectile dysfunction, and men with erectile dysfunction who did or did not seek treatment for their sexual dysfunction. Conclusions.?
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Erectile dysfunction (ED), also called impotence, affects most men at some point during their lifetime. However, chronic impotence may indicate a medical condition, such as heart disease, high blood pressure, high cholesterol, kidney disease, or diabetes.
Little is known about the function of PDE11A. Furthermore, selective inhibitors of PDE11 have not been reported. However, recent studies with a PDE11 knockout mouse model have been interpreted to suggest that PDE11 may be important for sperm development and function. Ejaculated sperm from knockout mice displayed slightly lower sperm concentration and decreased viability compared with controls, and the sperm had a lower rate of forward progression (Wayman et al., 2005). However, the animals were fertile. Moreover, it is still not clear whether PDE11 is expressed in reproductive tissue of the mouse.
The findings are published in this weeks issue of the Proceedings of the National Academy of Sciences.
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In addition, the risks of taking birth control pills may be greater if you are age 35 or older, overweight, have diabetes or a blood-clotting disorder, high blood pressure, or high cholesterol, reports Planned Parenthood. They recommend consulting a doctor right away if you experience chest or abdominal pain, leg soreness, jaundice, aura (seeing flashing lines before a headache), amenorrhea (no menstruation), or a lump in your breast.
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"This is very exciting -- the researchers have been working on this for a long time in a variety of different organs. It's not yet clinically available, but if it works and proves safe and effective, it would be a tremendous advance," said Dr. Ira Sharlip, a spokesman for the American Urological Association and a clinical professor of urology at the University of California, San Francisco.
Several laboratory tests can help diagnose ED. Tests for systemic diseases include blood counts, urinalysis, lipid profile, and measurements of creatinine and liver enzymes. Measuring the amount of free testosterone in the blood can yield information about problems with the endocrine system and is indicated especially in patients with decreased sexual desire.
Erectile dysfunction. This diagram depicts a cross-section of penile anatomy and is used to instruct patients in the technique of administering intracorporal medications.
Surgical Care A small number of healthy young men have developed ED as a result of trauma to the pelvic arteries. Revascularization procedures such as rotating the epigastric artery, or even smaller vessels, into the corpora have been attempted. The long-term results have been marginal.
Possible blindness due to nonarteritic anterior ischemic optic neuropathy and cilioretinal artery occlusion caused by PDE-5 inhibitors has been a concern. This is an extremely rare event, with only a handful of reported cases from the tens of millions of patients using PDE-5 inhibitor medications. This risk may be increased if the PDE-5 medication is misused or overdosed.
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